The Systematic Literature Review: Foundation of Evidence-Based Nursing
A systematic literature review (SLR) is a rigorous, reproducible method for identifying, evaluating, and synthesizing all relevant research on a specific clinical question. Unlike narrative reviews, SLRs follow explicit protocols that minimize bias and maximize comprehensiveness.
Why Systematic Reviews Matter in Nursing
Systematic reviews sit at the top of the evidence hierarchy. They inform clinical guidelines, policy decisions, and nursing practice standards. For nursing scholars, mastering the SLR process is essential for:
Dissertation literature review chaptersStand-alone publishable reviewsEvidence synthesis for EBP projectsGrant applications requiring evidence summariesThe PRISMA Framework
The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) provides a 27-item checklist and four-phase flow diagram that structures your review process. Following PRISMA ensures your review meets journal publication standards.
The Four PRISMA Phases:
1. Identification
Conduct comprehensive searches across multiple databases. For nursing research, essential databases include:
CINAHL Complete: The primary nursing and allied health databasePubMed/MEDLINE: Biomedical literature with MeSH indexingCochrane Library: Gold standard for systematic reviewsPsycINFO: Essential for mental health and behavioral topicsWeb of Science: Citation tracking and impact analysisDevelop your search strategy using controlled vocabulary (MeSH terms in PubMed, CINAHL Headings) combined with keyword searching. For detailed guidance on search optimization, see our Advanced Nursing Keywords guide.
2. Screening
Apply inclusion and exclusion criteria systematically:
Define eligible study designs (RCTs only? Include quasi-experimental?)Set population parameters (age, clinical setting, diagnosis)Establish date range and language restrictionsUse two independent reviewers to reduce screening bias3. Eligibility
Full-text review of remaining articles:
Assess each article against your complete inclusion criteriaDocument reasons for exclusion at this stageResolve disagreements between reviewers through discussion or a third reviewer4. Inclusion
Final articles included in your synthesis:
Extract data systematically using a standardized formAssess quality/risk of bias using validated tools (JBI, CASP, Cochrane RoB)Synthesize findings narratively or, if appropriate, through meta-analysisCritical Appraisal Tools for Nursing Research
Select your appraisal tool based on study design:
JBI Critical Appraisal Tools: Comprehensive suite covering 13 study designsCASP Checklists: Widely used, available for multiple designsCochrane Risk of Bias Tool (RoB 2): Specifically for randomized trialsNewcastle-Ottawa Scale: For observational studiesWriting Your Literature Review Chapter
Structure for a Dissertation:
Introduction: State the purpose and clinical significanceMethods: Describe your search strategy, databases, inclusion/exclusion criteriaResults: Present the PRISMA flow diagram, study characteristics table, and synthesisDiscussion: Interpret findings, identify gaps, and justify your studyConclusion: Summarize the state of evidence and implications for practiceTips for Scholarly Writing:
Use a synthesis matrix to organize themes across studiesPresent findings thematically rather than study-by-studyIdentify and explicitly address gaps in the literatureConnect your synthesis back to your theoretical frameworkFrom Review to Publication
A well-conducted systematic review is highly publishable. Top nursing journals for systematic reviews include:
*Journal of Advanced Nursing**Worldviews on Evidence-Based Nursing**International Journal of Nursing Studies**Nursing Research*For publication strategy guidance, explore our Publication Strategies resource. Our Evidence Synthesis services provide expert support for PRISMA-guided reviews at every stage.
Tools to Streamline Your Review
Covidence: Purpose-built for systematic review managementRayyan: Free, AI-assisted screening toolZotero: Reference management (see our [Zotero Plugins guide](/blog/zotero-plugins-nursing-researchers))RevMan: Cochrane's review authoring toolReady to start your systematic review? Our evidence synthesis mentors can guide you from protocol development to publication.